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Recent Articles

Myofilament-associated proteins with intrinsic disorder (MAPIDs) and their resolution by computational modeling

Peter M. Kekenes-Huskey, Bin Sun
Quarterly Review of Biophysics
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Toward bedside computation of myocardial infarction risk using noninvasive analysis of patients living with coronary artery disease

Peter M. Kekenes-Huskey
American Journal of Physiology-Heart and Circulatory Physiology (Jan 2023)
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Mutation-Specific Differences in Kv7.1 (KCNQ1) and Kv11.1 (KCNH2) Channel Dysfunction and Long QT Syndrome Phenotypes

Peter M. Kekenes-Huskey , Don E. Burgess , Bin Sun , Daniel C. Bartos , Ezekiel R. Rozmus , Corey L. Anderson , Craig T. January , Lee L. Eckhardt , and Brian P. Delisle
International Journal of Molecular Sciences (Jul 2022)
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Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium

Martijn van de Locht, Sandra Donkervoort, Josine M. de Winter, Stefan Conijn, Leon Begthel, Benno Kusters, Payam Mohassel, Ying Hu, Livija Medne, Colin Quinn, Steven A. Moore, A. Reghan Foley, Gwimoon Seo, Darren T. Hwee, Fady I. Malik, Thomas Irving, Weikang Ma, Henk L. Granzier, Erik-Jan Kamsteeg, Kalyan Immadisetty, Peter Kekenes-Huskey, José R. Pinto, Nicol Voermans, Carsten G. Bönnemann, and Coen A.C. Ottenheijm
The Journal of Clinical Investigation (Mar 2021)
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Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy

Mayra A. Marques, Maicon Landim-Vieira, Adolfo H. Moraes, Bin Sun, Jamie R. Johnston, Karissa M. Dieseldorff Jones, Elio A. Cino, Michelle S. Parvatiyar, Isela C. Valera, Jerson L. Silva, Vitold E. Galkin, P. Bryant Chase, Peter M. Kekenes-Huskey, Guilherme A. P. de Oliveira, and Jose Renato
Chemical Science (Apr 2021)
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Assessing the Role of Calmodulin's Linker Flexibility in Target Binding

Bin Sun and PKH
International Journal of Molecular Science (Apr 2021)
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Simulation-Based Characterization of Electrolytes and Small Molecule Diffusion in Oriented Mesoporous Silica Thin Films

Bin Sun, Ryan Blood, Selcuk Atalay, Dylan Colli, Stephen E. Rankin, Barbara L. Knutson and PKH
Springer Series in Materials Science.
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Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 KCNH2 (hERG) Mutations and Identifying New Patients

Makoto Ono, Don E. Burgess, Elizabeth A. Schroder, Claude S. Elayi, Corey L. Anderson, Craig T. January, Bin Sun, Kalyan Immadisetty, Peter M. Kekenes-Huskey, and Brian P. Delisle
Biomolecules (Aug 2020)
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Co-localization and confinement of ecto-nucleotidases modulate extracellular adenosine nucleotide distributions

Hadi Rahmaninejad, Tom Pace, Shashank Bhatt and PKH
PLOS Computational Biology (Apr 2020)
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Molecular Basis of S100A1 Activation and Target Regulation within Physiological Cytosolic Ca2+ Levels

Sun, Bin and PKH
Frontiers in Molecular Biosciences (Apr 2020)
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Calmodulin-Calcineurin Interaction beyond the Calmodulin-Binding Region Contributes to Calcineurin Activation

Bin Sun, Darin Vaughan, Svetlana Tikunova, Trevor P Creamer, Jonathan P Davis, Peter M Kekenes-Huskey
Biochemistry, 58(39):4070-4085 (2019)
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Thermodynamics of Cation Binding to the Sarcoendoplasmic Reticulum Calcium ATPase Pump and Impacts on Enzyme Function

Sun, Bin and PKH
JCTC, 15(4):2692 (2019)
PDF | DOI | PMID: 17025933

Simulation of P2X-mediated calcium signalling in microglia

Chun, Byeong Jae and PKH
The Journal of Physiology, 597(3):799-818 (2019)
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A Matched-Filter-Based Algorithm for Subcellular Classification of T-System in Cardiac Tissues

Colli, Dylan F., and PKH
Biophysical Journal, 116(8):1386-1393 (2019)
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Electrostatic control of calcineurin's intrinsically-disordered regulatory domain binding to calmodulin

Sun, Bin and PKH
Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(12):2651-2659 (2018)
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